Radboud university medical center is one of eight university medical centers in The Netherlands. With nearly 9,000 employees and 3,000 students, Radboudumc combines patient care, research, and education/training. Neuroscience research in Nijmegen is concentrated in the Donders Institute for Brain, Cognition and Behaviour. The Donders Institute is a world-renowned centre of neuroscience research expertise. We are a relatively young institute with an enterprising spirit and an excellent track record of research on Brain, Cognition and Behaviour. Over 500 researchers work here on unravelling the mechanisms of the brain.

The unique set-up provided by the joint efforts of the Departments of Psychiatry, Human Genetics and Cognitive Neuroscience under the Donders Institute for Brain, Cognition and Behaviour of the Donders institute will allow us to develop biomarkers that integrate pre-clinical and clinical studies in a manner that will allow for the creation of personalized treatments along with objective measures of diagnostic status. This group includes world-class researchers and opinion leaders in the field of child psychiatry, human molecular genetics and statistical genetics/machine learning. Professor Barbara Franke (Departments of Psychiatry & Human Genetics) is a renowned expert in the molecular underpinnings of ADHD. Professor Jan Buitelaar (Department of Cognitive Neuroscience) is an opinion leader on neuropsychiatric disorders as ADHD and ASD across the lifespan, and expert in neuropsychology and neural underpinnings of ADHD and ASD. Dr Jeffrey Glennon (Department of Cognitive Neuroscience) has a strong track record of forming and leading translational research consortia in neuropsychiatry. RUMC will (co-)coordinate WP7 and WP9 and participate in WP2,3,4,5,6 and 8. Within WP7 we will generate predictive biomarkers for disease and response to treatments using methods from machine learning and diagnostic accuracy analysis. RUMC will lead the development of dissemination strategies for CoCA science and other products (WP9), and contribute to the development of specialized training courses on project topics for CoCA researchers. RUMC will also ensure that project-wide ethical conduct will be monitored and supported by an internal ethics board and that CoCA will comply with all legal regulations and recommendations of the European Union, national legislation and local ethics committees.